Do Your Capsules Contain Colourings or Titanium Dioxide (TiO₂)?

“The drug company capsules have colourings that give me palpitations.”

That was a comment from one of our customers. They bought empty capsules from us because they wanted an alternative to the coloured capsule shell supplied with their product.

It is an easy detail to miss. When most of us check a medicine or supplement, we look at the active ingredient and the dose. We rarely look at the capsule shell. But the shell has its own ingredients too.

What is actually in the capsule shell?

Depending on the manufacturer, a capsule shell may contain gelatin or HPMC, colourants, opacifying ingredients, printing inks and other excipients. Titanium dioxide — TiO₂, also known as E171 — has also been widely used to make capsules and tablets white or opaque.

TiO₂ is no longer authorised as a food additive in the EU, although it continues to be permitted in medicinal products. So seeing TiO₂ on a medicine label does not by itself mean there is something wrong with the medicine. The point is simpler: if you are trying to avoid a particular colouring or excipient, check the shell as well as the contents.

Why some customers look for a plain capsule

People come to us for different reasons. Some are vegan. Some want a transparent capsule. Some want to avoid artificial colourings. Others specifically ask us for TiO₂-free capsules.

If that is what you are looking for, a clear HPMC capsule is often the simplest choice. There is no need for a white opacifier if you are happy for the capsule to be transparent.

Can you simply move your medicine into another capsule?

Not always. This is important.

A capsule is sometimes more than a container. The original formulation may be designed to release its contents in a particular way or at a particular place in the digestive system. Modified-release, delayed-release and gastro-resistant medicines need particular care.

If you are taking a prescription medicine, do not change the capsule shell just because another shell looks cleaner or has fewer ingredients. Ask your pharmacist or doctor whether changing the outer capsule is appropriate for that particular product.

TiO₂-free empty capsule options

For customers who simply need an empty capsule for self-filling, we stock a wide range of clear and TiO₂-free shells.

Our Size 00 clear HPMC vegetarian capsules are a straightforward transparent option. We also stock European-made Vcaps® Plus clear capsules, as well as TiO₂-free Vcaps® Plus capsules in different sizes and colours.

If you prefer some colour without TiO₂, for example, see our Vcaps® Plus Size 00 Blue Clear TiO₂-free capsules. We also carry other transparent and naturally coloured options.

One small thing worth checking

If a capsule does not agree with you, most people naturally suspect the ingredient inside. Sometimes it is worth reading the full ingredients list and checking the shell too.

If you are unsure which empty capsule to choose, contact us before ordering. Tell us the size you currently use and what you need the capsule for, and we can help you find the most suitable option.

Please note: Empty capsules are not a substitute for medical advice. Do not alter a prescription medicine, crush protected pellets or change a modified-release formulation unless a doctor or pharmacist has confirmed that it is appropriate.

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Customer Reviews

I've been using DR caps from pure capsules for a few years

I have been using the clear DR capsules from pure capsules for three years now. Like many others leaving reviews, I have a chronic UTI and I'm on hiprex and long term antibiotics. In order to protect my stomach I encapsulate all of these drugs in a 000 capsule which fits hiprex and coamoxiclav. The service that Bob and his team gives is first class. Quick to answer emails and the capsules are sent out very quickly.
Date of experience: 4 August 2023

Excellent Delayed Release Capsules Would highly recommend this Company and…

Would highly recommend this Company and their delayed release capsules if you're on long term medication that affects your stomach. My symptoms are much improved and the staff couldn't be more friendly and helpful when processing orders. A truly professional service. Thank you.
Date of experience: 2 August 2023

This company is amazing

This company is amazing. They have acid resistant capsules, which I can put my medication in, and have literally been a life-saver. They are reasonably priced, available to purchase as a individual customer (instead of just being for businesses), and the capsules always arrive in good time. I have never had any issues with this company and highly recommend them.
Date of experience: 14 July 2023

God Send for cUTI long term medication

These have been a god send. My long term medication for CUTI (hiprex and antibiotics) are very difficult to take as harsh on the tummy causing nausea, burning, reflux etc. If i encapsulate them in the enteric coated capsules they don't release until they hit the small intestine so all them nasty side effected no longer happen. Without these i wouldn't be able to stay on my medication and be extremely unwell so I am very grateful these are available!
Date of experience: 1 August 2023
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